The original structure was a two-story Federal style frame house, built in 1826 and converted into a tavern in 1864. During Prohibition, by which time a third story and stucco finish had been added, the “Seven Doors” bar continued to operate as a speakeasy. Following the repeal of the Eighteenth Amendment, the bar was renamed Julius’.

During the 1950s, Julius’ became known as a gathering place for gay New Yorkers, despite its management’s harassment of gay customers, under the auspices of liquor regulations prohibiting the sale of alcohol to “disorderly” customers (gay men were considered intrinsically disorderly).

In 1966, a group of gay activists and members of the Mattachine society held a “sip-in” to challenge the discriminatory law: after first identifying themselves as homosexuals, they ordered drinks from the Julius’ bartender who then refused service (the New York Times headline read “3 Deviates Invite Exclusion by Bars”). The men successfully challenged the New York State Liquor Authority in court, winning a ruling that guaranteed gay New Yorkers the right to peaceful assembly, thereby opening the door to legal, licensed gay bars.