The Stonewall Inn, site of the 1969 Stonewall riots, 1969.

The buildings at 51-53 Christopher Street were constructed in the 1840s as stables. In 1930 the two buildings were given a unified first floor of an Arts & Crafts style brick and stucco facade. The Stonewall Inn opened in 1967 and became a popular bar for the LGBT community.

In the early morning of June 28th, 1969 the police raided the bar (as they often did to gay establishments in the 1960s). The patrons of the bar did not disperse as ordered but instead fought back, angrily remaining on the streets in front of the bar, growing in numbers, and chanting at the rough treatment of those arrested. The Stonewall Riots (sometimes referred to as the Stonewall Uprising) lasted for the next six days and included demonstrations that encompassed the surrounding blocks. This event is considered the beginning of the modern LGBT right movement.

The buildings (today only no. 53 is the Stonewall Inn, an iteration that opened in 1993) are a part of the Greenwich Village Historic District, designated in 1969. In 2000 it was the first LGBT-related location to be named to the National Register of Historic Places and in 2015 an individual landmark designation was enacting, marking its cultural importance and making it the first landmark in New York City to be recognized on the basis of its status in LGBT history.