The New York Association for the Blind, today known as the Lighthouse Guild, was founded to provide "Light through Work." The association, which still operates today, is dedicated to advocacy and vision rehabilitation for the blind.

The foundation was established in 1903 by sisters Winifred and Edith Holt. It began at first as the "Lighthouse Free Ticket Bureau," which gave free concert tickets to blind children. The Holts were inspired by a similar project while visiting Italy. Looking to establish a program in their hometown, Winifred and Edith Holt started their own project. An article in the New York Times, dated January 13, 1907, wrote that: "When Misses Winifred and Edith Holt established a ticket bureau for the blind four years ago their sole thought was that they might relieve the somber lives of these sufferers," however, "it seemed that something more thoroughgoing should be attempted." Thus, the "Lighthouse Free Ticket Bureau" was transformed into the New York Association for the Blind, which offered education, vocational training, job placement, and recreation. The Association was modeled after a settlement house, which Winifred Holt was familiar with: she had been a regular volunteer at houses on the Bowery before dedicating her life to aiding the visually impaired. The Holt's charitable organization was formally incorporated as The New York Association for the Blind in 1906.

In addition to founding the Association, Winifred also campaigned for the first census of blind residents in New York. The census counted over nine-thousand New York residents who were visually impaired. She also helped found the New York State Commission for the Blind and Visually Handicapped. In 1914, Holt was recognized for her ceaseless social welfare work and awarded a gold model by the National Institute of Social Sciences.

Within the Association for the Blind, Winifred and Edith served as the secretary and recording secretary of the Association, respectively. The poet Richard Watson Gilder served as president with vice-president Helen Keller.

The Association started, at first, in the Brownstone home of the Holts, at 44 East 78th Street. They employed teachers who were visually impaired and therefore had a greater understanding of what it meant to instruct those who were also blind. Edith and Winifred came to a quick understanding that many of those who were blind needed steady employment in addition to educational services. In response, they converted their family Brownstone into a space for women to work and opened a workshop for men at East 42nd Street. In these spaces, men and women produced sellable wares, such as brooms, brushes, furniture, and mats, all of which would be sold on their behalf. According to the Times, "the home of the Misses Holt is a hive of workers engaged in advancing the interests of the blind in many ways." Additionally, adults were trained in the realm of clerical, sales, and business work. The program grew so quickly that an expansion known as the Bourne Workshop was opened at East 35th Street in 1912.

While providing employment, training, and education for adults, the New York Association for the Blind also took care of children. Various outdoor summer camps for children were opened around the state. Winifred also lobbied the New York Department of Education to allow visually impaired children to be admitted into public schools for the first time.

With the onset of World War I, and, seeing the success of the program in New York City, Winifred Holt worked to expand the Association onto the world's stage. Le Phare de Bordeaux was opened in France in 1915, as were offices, or "Lighthouses," in Paris, Rome, Warsaw, China, Japan, the Middle East, India, and South America, thus making the Association an international foundation. The New York Association for the Blind took on the name Lighthouse Incorporated in 1989 and was later re-named Lighthouse International. In 2005, the Guild celebrated its 100th anniversary. The offices of the Lighthouse Guild are now located at 250 West 64th Street.