St. Jerome's Catholic Church was built in 1899-1900 to the designs of the architectural firm Delhi and Howard. The cost of the building was $100,000, a considerable sum for the turn of the 20th century. The Italianate / Baroque Revival building can house a crowd of more than 1400 parishioners. The church is a part of the Mott Haven Historic District, which was designated in 1969. The main thoroughfare of the district, Alexander Avenue (where the church sits on the corner with 138th Street) was once known as "Irish Fifth Avenue."