New York University Main Building, February 1928.

Constructed in 1892-1895 as the Main Building of the New York University campus replaced a previous 1835 Gothic Revival structure on the site. Alfred Zucker, the German born architect of the building retained the foundation and a number of elements of the early structure. The impetus for this new building was perhaps less pedagogical than one might imagine. According to the AIA Guide the new building was constructed to accommodate a well paying tenant, the American Bank Note Company. That firm occupied the lower seven floors while the upper floors were used as the main administrative offices and the schools of law, commerce and pedagogy. Following the end of the First World War, the increase in student body necessitated the school taking over the entirely of the building.

In 2002 a bequest of $150 million by Julius Silver, a College of Arts and Science alumnus, prompted the building to be renamed the Silver Center for Arts and Science.