Man and microbes have always co-habited, and their relationship has had a profound influence on human history—especially in cities, the crossroads of the movements of people, goods, and germs. Germ City: Microbes and the Metropolis explores the complex story of New York’s long battle against infectious disease—a fight involving government, urban planners, medical professionals, businesses, and activists.

Jews’ Hospital in the City of New York (later Mount Sinai), sketch ca. 1866. The hospital that would become Mount Sinai opened on June 5, 1855, in a townhouse on West 28th Street. As its original name suggests, Jews’ Hospital served the needs of Jewish patients — and employed Jewish doctors — at a time when other hospitals in the city refused service. Non-Jewish patients were admitted in cases of emergency, as were Union soldiers wounded in the Civil War. In 1866, hospital directors adopted the new name Mount Sinai, signaling that patients of all backgrounds were welcome. In the early 1870s, the hospital moved to a new and larger facility at Lexington Avenue and 66th Street.