The Hotel Grosvenor Apartments were constructed in 1926 on the site of the 1876 Grosvenor Hotel. The original hotel was one of the earliest businesses in the fashionable mansion district.

39 Fifth Avenue ca. 1923 Emery Roth designed this 14-story apartment building, his first in Greenwich Village, in 1922. It was the first of many of the larger apartment houses which would line this part of Fifth Avenue, typically replacing the 19th-century mansions which originally lined the thoroughfare. It is clad in Flemish bond brick and is restrained in its ornament with the exception of the multi-colored terra-cotta loggias at the third and the eleventh and twelfth floors.